Viscoelasticity of dynamically fixed bioprosthetic valves. II. Effect of glutaraldehyde concentration
نویسندگان
چکیده
منابع مشابه
Thrombosis of Bioprosthetic Valves
O ver the 5 decades that bioprosthetic valves (BPVs) have been commonly implanted, the frequency of superimposed thrombosis has been thought to be negligible (1). Thus, early echocardiographic follow-up of patients with BPVs has been sparse, and chronic anticoagulation was mostly avoided. After the baseline post-operative study, current guidelines state that “patients with bioprosthetic valves ...
متن کاملAlkaline phosphatase activity of glutaraldehyde-treated bovine pericardium used in bioprosthetic cardiac valves.
Bioprosthetic valves fail frequently because of pathological mineralization, a process that begins in cell remnants of the glutaraldehyde (GLUT) fixed tissue. Other pathological cardiovascular calcification and physiological mineralization in skeletal/dental tissues are both largely initiated in cell-derived membranous structures (often called "matrix vesicles"), and the enzyme alkaline phospha...
متن کاملMechanism of efficacy of 2-amino oleic acid for inhibition of calcification of glutaraldehyde-pretreated porcine bioprosthetic heart valves.
BACKGROUND Calcification is a frequent cause of the clinical failures of glutaraldehyde-pretreated bioprosthetic heart valves (BPHV) fabricated from glutaraldehyde-cross-linked porcine aortic valves. 2-Amino oleic acid (AOA) has been shown in previous in vivo studies to be a promising anticalcification agent. Our objective was to investigate the mechanism of calcification inhibition mediated by...
متن کاملBioprosthetic valves and laudable inflammation?
from the University of Alberta (Canada) report a series of animal experiments designed to test the mythic role of gluteraldehyde in preventing recognition of bioprosthetic heart valve antigenicity with subsequent rejection and failure. Gluteraldehyde–cross-linked xenograft tissues (initially porcine) have been used in the manufacturing of stented (and now stentless) heart valves since 1970. Ori...
متن کاملComparative hydrodynamic evaluation of bioprosthetic heart valves.
BACKGROUND AND AIM OF STUDY Pressure gradients across cardiac valve prostheses have been identified as one of the most important performance measures in valve replacement surgery. Specifically in aortic valves, these gradients influence reduction of left ventricular hypertrophy and are postulated to influence long-term survival. The correct choice of replacement valve is hampered by a lack of u...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1997
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(97)70327-1